Education

• M.D., University of California, Irvine, 1988
• B.A., Neurobiology, UC Berkeley, 1983 (honors)

About

John Olichney is a board-certified behavioral neurologist who specializes in diagnosis, treatment and study of cognitive disorders and neurodegenerative diseases that typically are associated with aging, including Alzheimer's disease and other memory disorders.

Research Focus

Dr. Olichney conducts research examining the mechanisms of language and memory using electrophysiologic and neuroimaging techniques. His laboratory is developing and validating techniques and analytic methods sensitive to the memory and language impairments that are characteristic of Alzheimer's disease and other neurodegenerative disorders.

Lab

Cognitive Electrophysiology and Neuroimaging Lab (Olichney)

Publications

Olichney JM, Xia J, Church KJ, & Moebius HJ. Predictive power of cognitive biomarkers in neurodegenerative disease drug development: Utility of the P300 event-related potential. Neural Plasticity. 2022 Nov 8; PMCID: PMC9666049. PMID: 36398135.

Sapkota S, Erickson K, Harvey D, Tomaszewski‐Farias SE, Olichney JM, et al. Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 2022 Sept 1; 14(1), e12349.

Babiloni C, Arakaki X, Azami H, Bennys K, Blinowska K, Bonanni L…Olichney JM, et al. Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panel. Alzheimer's Dement. 2021 Apr 15. 17: 1528– 1553. DOI: 10.1002/alz.12311.

Xia J, Mazaheri A, Segaert K, Salmon DP, Harvey D, Shapiro K, Kutas M, Olichney JM. Event-related potential and EEG oscillatory predictors of verbal memory in mild cognitive impairment. Brain Commun. 2020 Dec 10;2(2):fcaa213. doi: 10.1093/braincomms/fcaa213. PMCID: PMC7749791. PMID: 33364603. 

Babiloni C, Blinowska K, Bonanni L… Olichney JM, et al. What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons. Neurobiol Aging. 2020 Jan;85:58-73. DOI: 10.1016/j.neurobiolaging.2019.09.008. Epub 2019 Sep 19. PMID: 31739167.

Maillard P, Fletcher E, Singh B, Martinez O, Johnson DK, Olichney JM, Farias ST, DeCarli C. Cerebral white matter free water: A sensitive biomarker of cognition and function.  Neurology. 2019 May 7;92(19):e2221-e2231. doi: 10.1212/WNL.0000000000007449. Epub 2019 Apr 5. PMID: 30952798: PMCID: PMC6537135.

Mazaheri A, Segaert K, Olichney J, Yang JC, Niu YQ, Shapiro K, Bowman H.  EEG oscillations during word processing predict MCI conversion to Alzheimer’s disease. Neuroimage: Clinical. 2017 Oct 9;17:188-197. doi: 10.1016/j.nicl.2017.10.009. PMID: 29159036.

Yang JC, Rodriguez A, Royston A, Niu YQ, Avar M, Brill R, Simon C, Grigsby J, Hagerman RJ, Olichney JM. Memantine Improves Attentional Processes in Fragile X-Associated Tremor/Ataxia Syndrome: Electrophysiological Evidence from a Randomized Controlled Trial. Scientific Reports. 2016. PMID: 26898832 PMCID: PMC4761982 www.nature.com/articles/srep21719.

Olichney, J. M., Pak, J., Salmon, D. P., Yang, J. C., Gahagan, T., Nowacki, R., . . . Iragui-Madoz, V. J. (2013). Abnormal P600 word repetition effect in elderly persons with preclinical Alzheimer’s disease. Cognitive Neuroscience 4(3–4), 143–51. doi:10.1080/17588928.2013.838945

Yang, J. C., Simon, C., Niu, Y. Q., Bogost, M, Schneider, A., Tassone, F., . . . Olichney, J. M. (2013). Phenotypes of hypofrontality in older female fragile X premutation carriers. Annals of Neurology 74(2), 275-83. doi:10.1002/ana.23933

Olichney, J. M. (2013). Test-retest reliability and stability of N400 effects: Implications for the study of neuropsychiatric and cognitive disorders. Clinical Neurophysiology 124(4), 634–35.

Bakken, T. E., Roddey, J. C., Djurovic, S., . . . & Olichney, J. (2012) Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proceedings of the National Academy of Sciences 109, 3985–90.

Kaur, B., Olichney, J., Harvey, D., DeCarli, C., & Sabbagh, M. (2013, July–September). Extrapyramidal signs by dementia severity in Alzheimer's disease and dementia with Lewy bodies. Alzheimer Disease and Associated Disorders 27(3), 226–32. doi: 10.1097/WAD.0b013e31826f040d

Teaching

Dr. John Olichney teaches medical students, residents and fellows in behavioral neurology, dementia, and general neurology. He teaches cognitive neuroscience research methods to research fellows, graduate students and undergraduates.

Awards

2000 – 2003           NARSAD Young Investigator Award

1997 – 1999           NARSAD Young Investigator Award

1995 – 2001           NIH Physician Scientist Award (National Institute on Aging)

1987                      Honors in Neurology Research