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CMB Monday Seminar (Methods)- Rene Scheeringa

Electrophysiological correlates of the human BOLD signal Simultaneous recording of hemodynamic and electrophysiological signals in monkeys and cats suggest that the hemodynamic effects observed with fMRI are a reflection are more tightly coupled to changes in local field potential activity than to spike rate changes. Especially gamma band activity was found to be tightly related to hemodynamic changes. The question arises whether these observations in animals also translate to the BOLD signal in humans during performance of cognitive tasks. In the work presented here we used simultaneous recorded EEG and fMRI to investigate how task related EEG power changes in different frequency bands (theta, alpha, beta and gamma power) relate to the changes in the BOLD signal.